Social Relationships and Inflammatory Markers in the MIDUS Cohort.
نویسندگان
چکیده
OBJECTIVE To better understand age and gender differences in associations of social relationships with chronic inflammation. METHOD Using a sample of middle-aged and older adults ( N = 963) from the Midlife Development in the United States (MIDUS) biomarker project, we examined interactions of age and gender with structural and functional social network measures in predicting interleukin-6 (IL-6) and C-reactive protein (CRP). RESULTS Significant interactions involving age and gender showed that social support was associated with lower IL-6 in older women, whereas perceived positive relationships and social integration were related to lower IL-6 in both men and women of advanced age. Functional measures were associated with higher CRP in both men and women after adjustment for health conditions and behaviors, with some further variation by age. DISCUSSION Greater social support may be related to lower IL-6 in older women. Further research is needed to understand observed associations of social support with higher CRP.
منابع مشابه
Pro-Inflammatory Cytokines in Omani Type 2 Diabetic Patients Presenting Anxiety and Depression
Background: The relationship of inflammatory cytokines with anxiety and depression has been reported, but their role in diabetic patients has not been fully elucidated. Objective: We examined whether an association between prevalence of anxiety and depression in Omani type-2 diabetic patients (n=30) and the levels of inflammatory markers such as IL-1β, TNF-α, IFN-γ and C-reactive protein (CRP) ...
متن کاملEvaluation of the Relationship between Hematological Indices and Cardiovascular Events in Isfahan Cohort Study
Background and Objective: Cardiovascular Disease (CVD) is the leading cause of death in developing countries. Inflammation significantly contributes to the process of atherosclerosis. Therefore, evaluating White Blood Cells (WBC) and platelet counts as markers of inflammatory as well as hematocrit as a marker of blood viscosity may predict coronary events. The present study aimed to evaluate th...
متن کاملIncome, education, and inflammation: differential associations in a national probability sample (The MIDUS study).
OBJECTIVE To examine the associations between income and education and three markers of inflammation: interleukin-6 (IL-6), C-reactive protein (CRP), and fibrinogen. Socioeconomic status is inversely linked with health outcomes, but the biological processes by which social position "gets under the skin" to affect health are poorly understood. METHOD Cross-sectional analyses involved participa...
متن کاملNight Shift Work, Sleep Quality, and Obesity
BACKGROUND The aims of this study were to examine the relationship between night shift work and sleep, to investigate the correlations with various biomarkers that show the influence of sleep on obesity, and ultimately, to analyze factors that have an impact on obesity. METHODS This study used data from the National Survey of Midlife Development in the United States II (MIDUS II study) and th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of aging and health
دوره شماره
صفحات -
تاریخ انتشار 2017